The nearest airport is VTU - Las Tunas Hermanos Ameijeiras, located 20.4 km south of La Guinea.
Other airports nearby include HOG - Holguin Frank Pais Intl (76.3 km south east), BYM - Bayamo Carlos Manuel De Cespedes (91.4 km south), MZO - Manzanillo Sierra Maestra (99.3 km south), CMW - Camaguey Ignacio Agramonte Intl (99.8 km west),