The nearest airport is VTU - Las Tunas Hermanos Ameijeiras, located 44.6 km south of Los Mameyes.
Other airports nearby include CMW - Camaguey Ignacio Agramonte Intl (82.2 km west), HOG - Holguin Frank Pais Intl (100.9 km south east), BYM - Bayamo Carlos Manuel De Cespedes (117.3 km south east), MZO - Manzanillo Sierra Maestra (120.3 km south),