The nearest airport is AVI - Ciego De Avila Maximo Gomez, located 68.0 km east of San Isidro.
Other airports nearby include SNU - Santa Clara Abel Santamaria (84.1 km north west), CFG - Cienfuegos Jaime Gonzalez (105.0 km west), CMW - Camaguey Ignacio Agramonte Intl (172.5 km east),