The nearest airport is AVI - Ciego De Avila Maximo Gomez, located 46.1 km east of San Isidro.
Other airports nearby include SNU - Santa Clara Abel Santamaria (83.6 km north west), CFG - Cienfuegos Jaime Gonzalez (124.5 km west), CMW - Camaguey Ignacio Agramonte Intl (163.5 km south east),