The nearest airport is VRA - Varadero Juan Gualberto Gomez Intl, located 63.2 km north west of San Isidro.
Other airports nearby include CFG - Cienfuegos Jaime Gonzalez (81.4 km south east), SNU - Santa Clara Abel Santamaria (104.5 km east), CYO - Cayo Vilo Acuna Intl (135.9 km south west), HAV - Havana Jose Marti Intl (154.7 km west),