The nearest airport is SAP - San Pedro Sula La Mesa Intl, located 117.9 km north east of Río Seco.
Other airports nearby include SAL - San Salvador El Salvador Intl (169.6 km south), CBV - Coban (171.2 km west), TEA - Tela (177.2 km north east), GUA - Guatemala City La Aurora (180.3 km west),