The nearest airport is HOG - Holguin Frank Pais Intl, located 28.7 km south of Los Güiros.
Other airports nearby include VTU - Las Tunas Hermanos Ameijeiras (63.1 km west), BYM - Bayamo Carlos Manuel De Cespedes (77.8 km south west), MZO - Manzanillo Sierra Maestra (115.0 km south west), SCU - Santiago De Cuba Antonio Maceo Intl (129.7 km south east),