The nearest airport is CMW - Camaguey Ignacio Agramonte Intl, located 26.4 km south west of San Nicolás.
Other airports nearby include VTU - Las Tunas Hermanos Ameijeiras (95.5 km south east), AVI - Ciego De Avila Maximo Gomez (130.7 km north west), MZO - Manzanillo Sierra Maestra (150.7 km south), HOG - Holguin Frank Pais Intl (160.9 km south east),