The nearest airport is CMW - Camaguey Ignacio Agramonte Intl, located 48.8 km north east of Santa Lucía.
Other airports nearby include AVI - Ciego De Avila Maximo Gomez (123.7 km north west), VTU - Las Tunas Hermanos Ameijeiras (126.7 km east), MZO - Manzanillo Sierra Maestra (141.3 km south east), BYM - Bayamo Carlos Manuel De Cespedes (176.4 km south east),