The nearest airport is EOH - Medellin Olaya Herrera, located 58.7 km south east of La Mesa.
Other airports nearby include MDE - Rio Negro Jose Maria Cordova (76.7 km south east), UIB - Quibdo El Carano (124.2 km south west), OTU - Otu (146.2 km east), BSC - Bahia Solano Jose Celestino Mutis (163.4 km west),