The nearest airport is TXA - Tlaxcala, located 31.0 km north west of Guadalupe.
Other airports nearby include PBC - Puebla Hermanos Serdan Intl (36.5 km west), MEX - Mexico City Licenciado Benito Juarez Intl (108.7 km west), TCN - Tehuacan (109.4 km south east), PCA - Pachuca Ingeniero Juan Guillermo Villasana (116.7 km north west),