The nearest airport is OAX - Oaxaca Xoxocotlan Intl, located 66.1 km north west of Santa Cruz.
Other airports nearby include HUX - Bahias Dehuatulco Bahias De Huatulco Intl (87.7 km south), PXM - Puerto Escondido Intl (113.8 km south west), TCN - Tehuacan (244.5 km north west), MTT - Minatitlan (249.6 km north east),