The nearest airport is TSL - Tamuin, located 98.1 km north of Santa Cruz.
Other airports nearby include PAZ - Poza Rico Tajin (126.7 km south east), PCA - Pachuca Ingeniero Juan Guillermo Villasana (127.8 km south), TAM - Tampico General Francisco Javier Mina Intl (138.0 km north east), QRO - Queretaro Intercontinental (186.9 km west),