The nearest airport is TSL - Tamuin, located 86.5 km east of Zapotillo.
Other airports nearby include SLP - San Luis Potosi Ponciano Arriaga Intl (139.1 km west), CVM - Ciudad Victoria General Pedro Jose Mendez Intl (164.8 km north east), TAM - Tampico General Francisco Javier Mina Intl (177.0 km east), QRO - Queretaro Intercontinental (200.0 km south),