The nearest airport is PIU - Piura Capitan Fap Guillermo Concha Iberico, located 98.1 km west of Guyupayú.
Other airports nearby include TYL - Talara Capitan Montes (180.2 km west), CIX - Chiclayo Capt Jose A Quinones Gonzales Intl (181.4 km south), TBP - Tumbes Pedro Canga (190.7 km north), MCH - Machala General Manuel Serrano (209.5 km north),