The nearest airport is IOA - Ioannina, located 22.4 km east of Despotikón.
Other airports nearby include CFU - Kerkyra/corfu Ioannis Kapodistrias Intl (58.2 km west), PVK - Preveza Aktio (91.9 km south), KSO - Kastoria Aristotelis (99.5 km north east), KZI - Kozani Filippos (124.7 km north east),