The nearest airport is CMW - Camaguey Ignacio Agramonte Intl, located 54.3 km south east of Misión.
Other airports nearby include AVI - Ciego De Avila Maximo Gomez (64.2 km north west), VTU - Las Tunas Hermanos Ameijeiras (159.8 km south east), SNU - Santa Clara Abel Santamaria (193.3 km north west), MZO - Manzanillo Sierra Maestra (199.9 km south east),