The nearest airport is EOH - Medellin Olaya Herrera, located 83.7 km south east of El Guamo.
Other airports nearby include MDE - Rio Negro Jose Maria Cordova (98.9 km south east), OTU - Otu (137.5 km east), UIB - Quibdo El Carano (152.4 km south west), BSC - Bahia Solano Jose Celestino Mutis (176.4 km south west),