The nearest airport is MDE - Rio Negro Jose Maria Cordova, located 60.5 km south west of Frailes.
Other airports nearby include OTU - Otu (66.2 km north east), EOH - Medellin Olaya Herrera (74.2 km west), EJA - Barrancabermeja Yariguies (142.3 km north east), MZL - Manizales La Nubia (168.2 km south),