The nearest airport is EOH - Medellin Olaya Herrera, located 53.9 km south east of La Mesa.
Other airports nearby include MDE - Rio Negro Jose Maria Cordova (71.3 km south east), UIB - Quibdo El Carano (128.4 km south west), OTU - Otu (139.7 km east), BSC - Bahia Solano Jose Celestino Mutis (170.0 km west),