The nearest airport is EOH - Medellin Olaya Herrera, located 71.9 km south east of Mesas.
Other airports nearby include MDE - Rio Negro Jose Maria Cordova (88.4 km south east), UIB - Quibdo El Carano (138.9 km south west), OTU - Otu (141.2 km east), BSC - Bahia Solano Jose Celestino Mutis (169.1 km west),