The nearest airport is PPN - Popayan Guillermo Leon Valencia, located 31.1 km east of San Luis.
Other airports nearby include GPI - Guapi Juan Casiano (113.7 km west), CLO - Cali Alfonso Bonilla Aragon Intl (124.2 km north east), PSO - Pasto Antonio Narino (134.2 km south), BUN - Buenaventura Gerardo Tobar Lopez (142.5 km north),