The nearest airport is REX - Reynosa General Lucio Blanco Intl, located 89.5 km north east of Guayacán.
Other airports nearby include MFE - Mcallen Mc Allen Miller Intl (100.8 km north east), MTY - Monterrey General Mariano Escobedo Intl (119.3 km west), NTR - Monterrey Del Norte Intl (134.3 km west), MAM - Matamoros General Servando Canales Intl (145.4 km east),