The nearest airport is BJX - Del Bajio Guanajuato Intl, located 80.1 km south of Mezquite.
Other airports nearby include SLP - San Luis Potosi Ponciano Arriaga Intl (81.3 km north east), AGU - Aguascalientes Jesus Teran Intl (88.1 km west), QRO - Queretaro Intercontinental (180.3 km south east), ZCL - Zacatecas General Leobardo C Ruiz Intl (181.4 km north west),