The nearest airport is PCA - Pachuca Ingeniero Juan Guillermo Villasana, located 67.1 km south east of Samayoa.
Other airports nearby include QRO - Queretaro Intercontinental (102.5 km west), MEX - Mexico City Licenciado Benito Juarez Intl (122.1 km south), TLC - Toluca Licenciado Adolfo Lopez Mateos Intl (137.5 km south), TXA - Tlaxcala (154.3 km south east),