The nearest airport is PCA - Pachuca Ingeniero Juan Guillermo Villasana, located 104.1 km south of San Simón.
Other airports nearby include TSL - Tamuin (113.1 km north), PAZ - Poza Rico Tajin (148.4 km east), QRO - Queretaro Intercontinental (149.2 km west), TAM - Tampico General Francisco Javier Mina Intl (172.5 km north east),