The nearest airport is VSA - Villahermosa C P A Carlos Rovirosa Intl, located 36.7 km north east of Santa Cruz.
Other airports nearby include TGZ - Tuxtla Gutierrez Angel Albino Corzo (133.4 km south), MTT - Minatitlan (164.7 km west), CME - Ciudad Del Carmen Intl (166.2 km north east),