The nearest airport is VSA - Villahermosa C P A Carlos Rovirosa Intl, located 41.4 km north east of Santa Cruz.
Other airports nearby include TGZ - Tuxtla Gutierrez Angel Albino Corzo (137.7 km south), MTT - Minatitlan (155.2 km west), CME - Ciudad Del Carmen Intl (171.3 km north east),