The nearest airport is MTY - Monterrey General Mariano Escobedo Intl, located 96.7 km north of Santa Cruz.
Other airports nearby include NTR - Monterrey Del Norte Intl (107.0 km north), SLW - Saltillo Plan De Guadalupe Intl (108.0 km north west), CVM - Ciudad Victoria General Pedro Jose Mendez Intl (178.2 km south east), REX - Reynosa General Lucio Blanco Intl (226.4 km north east),