The nearest airport is NTR - Monterrey Del Norte Intl, located 78.4 km south of Santa Cruz.
Other airports nearby include MTY - Monterrey General Mariano Escobedo Intl (87.2 km south), NLD - Nuevo Laredo Quetzalcoatl Intl (111.5 km north east), LRD - Laredo Intl (126.4 km north east), SLW - Saltillo Plan De Guadalupe Intl (138.8 km south west),