The nearest airport is TLC - Toluca Licenciado Adolfo Lopez Mateos Intl, located 64.0 km east of Santa Cruz.
Other airports nearby include MLM - Morelia General Francisco J Mujica Intl (101.2 km north west), MEX - Mexico City Licenciado Benito Juarez Intl (114.9 km east), CVJ - Cuernavaca General Mariano Matamoros (116.0 km south east), QRO - Queretaro Intercontinental (131.1 km north),