The nearest airport is REX - Reynosa General Lucio Blanco Intl, located 26.3 km east of Zopilote.
Other airports nearby include MFE - Mcallen Mc Allen Miller Intl (27.3 km north east), HRL - Harlingen Valley Intl (84.8 km east), MAM - Matamoros General Servando Canales Intl (101.5 km east), BRO - Brownsville South Padre Island Intl (107.4 km east),