The nearest airport is TGU - Tegucigalpa Toncontin Intl, located 76.1 km south west of Guillén.
Other airports nearby include LCE - La Ceiba Goloson Intl (117.4 km north), TEA - Tela (135.0 km north west), SAP - San Pedro Sula La Mesa Intl (137.7 km north west), RTB - Roatan Juan Manuel Galvez Intl (185.6 km north),