The nearest airport is TGU - Tegucigalpa Toncontin Intl, located 38.6 km south west of San Luis.
Other airports nearby include LCE - La Ceiba Goloson Intl (165.3 km north), SAP - San Pedro Sula La Mesa Intl (171.6 km north west), TEA - Tela (179.2 km north),