The nearest airport is AVI - Ciego De Avila Maximo Gomez, located 51.2 km west of Caimito Dos.
Other airports nearby include CMW - Camaguey Ignacio Agramonte Intl (70.6 km south east), VTU - Las Tunas Hermanos Ameijeiras (174.2 km south east), SNU - Santa Clara Abel Santamaria (180.7 km west), MZO - Manzanillo Sierra Maestra (217.8 km south east),