The nearest airport is AVI - Ciego De Avila Maximo Gomez, located 31.9 km north west of Cupeyes.
Other airports nearby include CMW - Camaguey Ignacio Agramonte Intl (86.5 km south east), SNU - Santa Clara Abel Santamaria (161.1 km north west), VTU - Las Tunas Hermanos Ameijeiras (192.1 km south east), CFG - Cienfuegos Jaime Gonzalez (196.7 km west),