The nearest airport is MZO - Manzanillo Sierra Maestra, located 16.0 km north west of Guasimilla.
Other airports nearby include BYM - Bayamo Carlos Manuel De Cespedes (44.5 km north east), VTU - Las Tunas Hermanos Ameijeiras (89.2 km north), HOG - Holguin Frank Pais Intl (96.5 km north east), SCU - Santiago De Cuba Antonio Maceo Intl (122.4 km east),