The nearest airport is HOG - Holguin Frank Pais Intl, located 48.8 km north west of Guayabero.
Other airports nearby include SCU - Santiago De Cuba Antonio Maceo Intl (55.3 km south), BYM - Bayamo Carlos Manuel De Cespedes (61.5 km west), GAO - Guantanamo Mariana Grajales (99.2 km south east), MZO - Manzanillo Sierra Maestra (111.4 km west),