The nearest airport is AVI - Ciego De Avila Maximo Gomez, located 35.4 km north of La Isidora.
Other airports nearby include CMW - Camaguey Ignacio Agramonte Intl (113.7 km east), SNU - Santa Clara Abel Santamaria (137.6 km north west), CFG - Cienfuegos Jaime Gonzalez (163.8 km west), VTU - Las Tunas Hermanos Ameijeiras (219.0 km east),