The nearest airport is CMW - Camaguey Ignacio Agramonte Intl, located 47.0 km north west of Las Mercedes.
Other airports nearby include VTU - Las Tunas Hermanos Ameijeiras (65.0 km east), MZO - Manzanillo Sierra Maestra (101.9 km south east), BYM - Bayamo Carlos Manuel De Cespedes (124.2 km south east), HOG - Holguin Frank Pais Intl (133.1 km east),