The nearest airport is MZO - Manzanillo Sierra Maestra, located 27.9 km north west of Madre Vieja.
Other airports nearby include BYM - Bayamo Carlos Manuel De Cespedes (47.6 km north east), VTU - Las Tunas Hermanos Ameijeiras (100.1 km north), HOG - Holguin Frank Pais Intl (101.0 km north east), SCU - Santiago De Cuba Antonio Maceo Intl (115.6 km east),