The nearest airport is BYM - Bayamo Carlos Manuel De Cespedes, located 38.3 km north west of Santa María.
Other airports nearby include SCU - Santiago De Cuba Antonio Maceo Intl (60.1 km east), HOG - Holguin Frank Pais Intl (72.6 km north), MZO - Manzanillo Sierra Maestra (75.7 km west), VTU - Las Tunas Hermanos Ameijeiras (110.7 km north west),