The nearest airport is PCA - Pachuca Ingeniero Juan Guillermo Villasana, located 93.4 km south of Guadalupe.
Other airports nearby include TSL - Tamuin (124.4 km north), QRO - Queretaro Intercontinental (141.0 km west), PAZ - Poza Rico Tajin (150.7 km east), MEX - Mexico City Licenciado Benito Juarez Intl (165.2 km south),