The nearest airport is NLD - Nuevo Laredo Quetzalcoatl Intl, located 86.2 km north of Guadalupe.
Other airports nearby include LRD - Laredo Intl (97.4 km north), NTR - Monterrey Del Norte Intl (113.2 km south west), MTY - Monterrey General Mariano Escobedo Intl (113.9 km south west), MFE - Mcallen Mc Allen Miller Intl (140.1 km south east),