The nearest airport is HMO - Hermosillo General Ignacio P Garcia Intl, located 64.9 km south west of Guadalupe.
Other airports nearby include GYM - Guaymas General Jose Maria Yanez Intl (163.0 km south), NOG - Nogales Intl (210.1 km north), CEN - Ciudad Obregon Intl (229.2 km south),