The nearest airport is HMO - Hermosillo General Ignacio P Garcia Intl, located 106.5 km south west of Guadalupe.
Other airports nearby include NOG - Nogales Intl (144.6 km north), FHU - Fort Huachuca Sierra Vista Muni Libby Aaf (181.3 km north), GYM - Guaymas General Jose Maria Yanez Intl (223.9 km south),