The nearest airport is NOG - Nogales Intl, located 79.6 km north east of San Manuel.
Other airports nearby include FHU - Fort Huachuca Sierra Vista Muni Libby Aaf (148.6 km north east), TUS - Tucson Intl (172.3 km north), HMO - Hermosillo General Ignacio P Garcia Intl (172.3 km south), DMA - Tucson Davis Monthan Afb (179.2 km north),