The nearest airport is TGU - Tegucigalpa Toncontin Intl, located 39.7 km west of Guapinol.
Other airports nearby include LCE - La Ceiba Goloson Intl (183.6 km north), SAP - San Pedro Sula La Mesa Intl (190.6 km north west), TEA - Tela (199.0 km north), MGA - Managua Intl (227.2 km south),