The nearest airport is SAL - San Salvador El Salvador Intl, located 104.1 km south of San Luis.
Other airports nearby include SAP - San Pedro Sula La Mesa Intl (158.4 km north east), GUA - Guatemala City La Aurora (178.9 km west), TGU - Tegucigalpa Toncontin Intl (183.0 km east), CBV - Coban (204.3 km north west),