The nearest airport is HOG - Holguin Frank Pais Intl, located 44.2 km south of La Isla.
Other airports nearby include VTU - Las Tunas Hermanos Ameijeiras (64.6 km west), BYM - Bayamo Carlos Manuel De Cespedes (91.6 km south), MZO - Manzanillo Sierra Maestra (125.5 km south west), SCU - Santiago De Cuba Antonio Maceo Intl (144.7 km south),